The Nigerian president's top media aide Garba Shehu tested positive for coronavirus on Saturday.
Shehu, who is in the immediate circle of 79-year-old President Muhammadu Buhari, announced the news, affirming that he is in isolation.
"I can only confirm that (I am) infected by COVID-19 and on treatment in isolation," Shehu said.
Media outlets reported that some of Buhari's aides and top officials have contracted the virus, including Information Minister Lai Mohammed.
However, Mohammed did not respond to calls for comment while a presidency spokesman declined to comment on whether any other official or minister was infected with the deadly virus.
Officials also did not reveal whether Buhari, who received a booster dose on Tuesday, has been tested negative or positive.
Notably, Buhari has recently attended summits in Dubai and Turkey along with some ministers after hosting South African President Cyril Ramaphosa last month just as the Omicron variant was detected in Southern Africa and Hong Kong.
Nigeria has so far recorded 234,709 confirmed cases with 2,993 deaths.
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