Barcelona announced on Sunday that midfielder Philippe Coutinho is set to miss the Champions League fixture with Juventus on Wednesday after injuring his left hamstring.
"The length of the 28-year-old's absence will "depend on how the injury evolves", according to Barca.
The Brazilian featured all 90 minutes of Barca's 3-1 loss to Real Madrid in El Clasico on Saturday.
The ex-Liverpool player spent the 2019-20 season on loan at Bayern Munich, and has made five starts this season.