Chinese scientists have developed a multivalent nanotechnology vaccine for the novel coronavirus disease “COVID-19”, which can protect against the deadly virus mutant infection.
And the Chinese “Xinhua” news agency reported today, Monday that scientists from Sun Yat-Sen University have designed a quadrivalent nano-vaccine that includes spike proteins from the first model of the SARS-CoV-2 virus, and the three main mutants are alpha, beta, and gamma.
A study recently published in the journal Nature Communications showed that the nanoparticles produced equivalent or superior antibodies that neutralized the mutated strains in mice and non-human primates with only a slight decrease in the neutralization titer against the main strain.
The scientists also tested the vaccine against the Omicron and Lambda mutants, as the two mutants slightly reduced the neutralizing ability of the vaccine-stimulated sera, suggesting that sera can elicit protective antibody responses on a large scale to the circulating variants.
