Caterpillar Fungus Shown to Inhibit Cancer Cell Growth

Recent research has revealed that a parasitic fungus, known as caterpillar fungus, could help slow the growth of cancer cells.

The fungus produces a chemical compound called cordycepin, which disrupts the cell growth signals that are often overactive in cancerous cells.

Scientists from the University of Nottingham’s School of Pharmacy made the breakthrough discovery, which could pave the way for new cancer treatments.

The study, published in FEBS Letters, demonstrated that cordycepin, produced by Cordyceps militaris—an orange fungus that infects caterpillars—interferes with genetic pathways that promote unchecked cell proliferation.

For centuries, caterpillar fungus has been used in traditional medicine and is considered a delicacy in parts of Asia.

The latest findings suggest that cordycepin has significant potential as a basis for developing novel cancer drugs.

Cornelia de Moor, a researcher at the university, commented, "Our findings validate cordycepin as a promising starting point for innovative cancer therapies.

Additionally, the data identifies specific genes whose activity can be monitored to gauge the drug's effectiveness in patients."

This discovery could lead to more targeted and effective cancer treatments, opening the door to further research into cordycepin-based therapies.