Paris Saint-Germain stars Neymar and Sergio Ramos have been left out of the team's squad for their Ligue 1 match Rennes on Friday, just four days before their Champions League game against Real Madrid.
Neymar has not played since November after suffering a ligament injury in November, whilst Ramos is recovering from a minor calf injury.
Coach Mauricio Pochettino has not ruled out Neymar making an appearance during Tuesday night's big clash against Los Blancos.
"We'll see if it can happen," Pochettino told the press. "That's the idea. All the big guys want to play in the big games.
"He already knows what it's like to arrive injured at these games and has the maturity to channel his energy and play in the best conditions when he's available."